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Dynamical regimes of excitable cells under pulsed electric fields: From excitation to electroporation

Nanosecond pulse electric fields (nsPEFs) are an established treatment modality for cancer and have emerged as a potential approach for deep brain stimulation and cardiac defibrillation. The concerns in these two applications are at odds. While pulsed-field electroporation applications aim to minimise excitation of surrounding neurons, therapies based on neuronal stimulation demand minimal…

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