Cancer cells hijack mitochondria from Bhlhe40+ T cells for immune evasion
Cancer cells hijack mitochondria from T cells via tunneling nanotubes (TNTs) to promote immune evasion, yet the underlying mechanisms of mitochondrial-loss remain poorly understood. Here, through targeted screening of relevant genes, we demonstrated that CD38 is a potent regulator of TNT formation through interaction with its cognate ligand, CD31. Conditional knockdown of Cd38 in murine models…
We haven't written up this one. bioRxiv has the full story — the link below goes straight to it.
