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Vitamin Derivative Pantethine Alleviates Psoriasis Symptoms in Small Human Trial

Researchers found that the vitamin B5 derivative pantethine prevented the development of psoriasis in mice, and in a small-scale trial in human psoriasis patients administering pantethine in combination with topical calcipotriol/betamethasone dipropionate helped to alleviate symptoms. The post Vitamin Derivative Pantethine Alleviates Psoriasis Symptoms in Small Human Trial appeared first on GEN -…

Vitamin Derivative Pantethine Alleviates Psoriasis Symptoms in Small Human Trial

A team of researchers from the State Key Laboratory of Biomedical Analysis in Beijing has discovered that the vitamin B5 derivative pantethine may help alleviate symptoms of psoriasis by limiting the activity of dendritic cells (DCs), immune cells linked to autoimmune diseases. In a small human trial, patients with psoriasis who took pantethine alongside topical treatments experienced improved symptoms, particularly those with higher initial blood cholesterol levels.

The study, published in the Journal of Experimental Medicine, suggests that metabolic pathways and their associated metabolites, like pantethine, could be promising targets for treating various autoimmune diseases, including psoriasis.

Written by urgent.news from GEN Biotechnology's reporting — not their text. Machine-written — may contain errors; check the original before relying on it.

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