Integrative Single-Cell Transcriptomics and Explainable AI for Disease Mechanism and Biomarker Discovery in Triple-Negative Breast Cancer
Invasion is an early step in the metastatic spread of triple-negative breast cancer (TNBC), yet cells within a single tumour or cell line differ in their capacity to invade, and it is unclear which transcriptional features distinguish cells that invade from those that do not. We re-analysed the public single-cell RNA-sequencing dataset GSE329526, in which ClonMapper-barcoded MDA-MB-231 cells were…
We haven't written up this one. bioRxiv has the full story — the link below goes straight to it.
