Genome-Wide Transcriptomics Uncovers a Lung-to-Aorta Inflammatory Program Driving Influenza-Induced Atherosclerosis Exacerbation
Influenza infection increases cardiovascular risk in individuals with pre-existing atherosclerosis, yet the genome-wide transcriptional basis of this association remains undefined. We performed bulk RNA sequencing of aorta and lung tissues from high-fat diet-fed Apoe-/- mice infected with influenza A/PR/8/34 versus PBS-treated controls at day 15 post-infection, identifying 6,828 differentially…
We haven't written up this one. bioRxiv has the full story — the link below goes straight to it.
