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Excluded Volume Effect-induced Shrinkage for Resolution Enhancement of Hydrogel Bioconstructs

Biofabrication of hydrogel materials is usually constrained by process-specific resolution limits. Here, we introduce excluded volume effect-induced shrinkage (EVER), a dehydration-enabled resolution enhancement strategy that achieves dimensional refinement via post-processing. In this approach, we treat biofabricated constructs with hydrophilic macromolecular crowding agent bath, with poloxamer…

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