Zhejiang Wenda Pharma reports Phase II BET inhibitor trial data
Zhejiang Wenda Pharma published Phase II clinical trial results at ESMO 2026 for oral BET inhibitor NHWD 870 HCl in patients with advanced NUT carcinoma
Zhejiang Wenda Pharma is set to present phase II clinical trial data for NHWD-870 HCl, an oral BET inhibitor, at the 2026 ESMO Annual Meeting. The study, conducted in Chinese patients with advanced NUT carcinoma (NC), revealed a 30% objective response rate (ORR) and a 47.5% disease control rate (DCR). The trial also showed median progression-free survival (PFS) and overall survival (OS) of 2.76 and 9.33 months, respectively.
NHWD-870 HCl, a novel oral BET inhibitor, has been granted breakthrough therapy designation by the China National Medical Products Administration (NMPA) for advanced thoracic NUT carcinoma.
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