Weight-loss surgery produces lasting diabetes remission, long-term study finds
People with type 2 diabetes were much more likely to achieve remission after weight-loss surgery than after intensive medical and lifestyle management, according to a long-term study. Researchers also identified patient characteristics linked to remission and to the likelihood of diabetes returning.
A long-term study published in Diabetes Care has found that weight-loss surgery significantly increases the likelihood of diabetes remission in people with type 2 diabetes compared to intensive medical and lifestyle management. The study, conducted by the Alliance of Randomized Trials of Medicine vs. Metabolic Surgery in Type 2 Diabetes (ARMMS-T2D), followed 262 participants for a median of 11 years, with some participants followed for up to 14 years.
Researchers found that 58% of participants who underwent metabolic-bariatric surgery achieved diabetes remission, compared to just 3% of those assigned to medical and lifestyle management. The study identified certain patient characteristics as being associated with remission and the likelihood of diabetes returning, such as shorter diabetes duration, no insulin use, and greater early weight loss.
The findings suggest that a patient's history of diabetes and response to treatment may help physicians assess the likelihood of remission and its potential duration, potentially allowing for surgery to be offered to the right people earlier.
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