Structural Determinants of the Energetic Barrier of Phospholipid Flip-Flop
Spontaneous phospholipid flip-flop sets the background against which flippases, floppases, and scramblases create and dissipate membrane asymmetry. How the associated free-energy barrier depends on lipid chemistry and on the surrounding membrane remains unclear, because experiments are few and contradictory and previous simulations covered only a small part of the lipidome. Here, we calculate…
We haven't written up this one. bioRxiv has the full story — the link below goes straight to it.
