Non-canonical proteoforms of the human fusiform gyrus in Alzheimers disease
For a long time, the protein coding potential of our genome was underestimated. Only 2% of the genome was thought to be coding for the protein while the rest was called non-coding and junk. The two main sources of biasness which resulted in underestimation were prioritising conservation and length of the open reading frames (ORFs). But recent Ribo-seq studies and high throughput quantitative…
We haven't written up this one. bioRxiv has the full story — the link below goes straight to it.
