Host brain infection induces RNAi epimutation in Mucor circinelloides and enhances blood-brain barrier invasion
Mucorales fungi cause mucormycosis, a rapidly progressive invasive fungal disease with high mortality, particularly in immunocompromised patients and in severe disseminated infections. Central nervous system involvement is among the most devastating manifestations of mucormycosis, yet the mechanisms that enable Mucorales to adapt to the brain environment remain poorly understood. In Mucor…
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