Hematoxylin and eosin (H&E) histology and spatial transcriptomics (ST) provide complementary tissue views, with H&E capturing morphology and ST measuring spatial gene expression. Together, they connect tissue architecture to molecular state. We present a multi-scale training framework for adapting pretrained H&E encoders from paired H&E and ST, producing ALHENA, which requires only H&E at…
In 1987, biologists captured the last free-flying condor to transfer it to captivity, and the largest flying North American bird species was officially declared extinct in the wild.
