Specification of Origins of DNA Replication Within Distinct Chromatin States in Human Cells
A comprehensive map of binding sites for the Origin Recognition Complex (ORC) in the human genome reveals relationships among replication licensing, chromatin state, three-dimensional genome organization, location of origins of DNA replication and DNA replication timing. Defining these relationships is essential for understanding how replication licensing is integrated with the broader…
We haven't written up this one. bioRxiv has the full story — the link below goes straight to it.
