Exploring the influence of mutation rates with stochastic perturbations on genome evolution
We present a stochastic version of the classical Luria-Delbruck mutation rate model using Ito calculus. Our model is used to explore implications of population growth with randomly varying mutation rates. By comparing the Itô version of the Luria-Delbruck mutation rate model to the deterministic we find that stochastic effects can have profound implications for genome evolution. In…
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