CST-Polα/primase, backed up by Rif1, protects telomeric ss-dsDNA junctions from damage recognition and resection
The yeast Cdc13-Stn1-Ten1 (CST) complex is critical for telomere length regulation and telomere protection. Recent studies further implicate Pol/primase (PP) as an essential partner of CST in executing these functions, but the mechanistic bases remain poorly understood. Using the pathogenic yeast Nakaseomyces glabratus, a model amenable to mechanistic dissection of CST-PP, we analyzed the…
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