Ancestral Quadruplication of Protein Kinase R in Tarsiers Hints Towards Novel Primate-Virus Innovations
Tarsiers, an elusive family of primates found in Indonesia and the Philippines, sit at an essential point in primate evolution, with their divergence between that of Strepsirrhini (lemurs) and Simiiformes (monkeys and apes). Through homology searches, we have discovered that tarsiers carry the first known case in primates of a gene expansion of protein kinase R (PKR), a kinase involved in the…
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