MiR-208b-3p is an upstream regulator of redox-associated cardiomyocyte survival
Background: Cardiac stress induces MYH6-to-MYH7 remodeling and activates redox-defense programs, but the regulatory mechanisms that distinguish adaptive from maladaptive stress responses remain incompletely defined. We investigated the role of miR-208b-3p, an intronic MYH7 microRNA, in cardiac stress adaptation. Methods and Results: We integrated myocardial transcriptomic and small RNA sequencing…
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