How do we monitor doxy-PEP impact and when should we consider revisiting guidelines?
by Yonatan H. Grad, Rachel Mittelstaedt, Remco P. H. Peters Summary points The 2026 WHO guidelines recommending doxycycline post-exposure prophylaxis (doxy-PEP) represent the first global antibiotic prophylaxis recommendation for bacterial sexually transmitted infections (STIs), with provisions for antimicrobial resistance (AMR) monitoring. Doxy-PEP should be governed as an adaptive intervention…
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