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Analysis of the impact of naturally-acquired immunity on <i>Shigella</i> vaccine performance to inform clinical trials: A simulation-based modeling study

by Avnika B. Amin, Maria Garcia Quesada, Daniel Trudell, Natalie E. Dean, Benjamin A. Lopman, James A. Platts-Mills, Elizabeth T. Rogawski McQuade Background Effective vaccines against Shigella , the leading bacterial cause of diarrheal disease globally, could prevent morbidity and mortality from shigellosis as well as limit antibiotic resistance. Several Shigella vaccine candidates are in late…

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