Voluntary wheel running selectively preserves skeletal muscle during pancreatic cancer cachexia despite persistent systemic alterations
Abstract Background Pancreatic ductal adenocarcinoma (PDAC) is frequently associated with cancer cachexia, involving alterations across multiple physiological systems. Whether distinct exercise paradigms similarly influence these compartments remains unclear. We compared voluntary wheel running (VWR) and treadmill running (TR) using an integrative physiological approach in a murine model of…
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