Roles of Interstitial Albumin in the Subcutaneous Delivery of Therapeutic Peptides
Subcutaneous administration of biotherapeutics is increasingly favoured for better safety profile, improved stability, and patient compliance compared with intravenous administration. Despite these advantages, the roles of extracellular matrix (ECM) components and interstitial proteins, particularly albumin, in the mechanisms governing therapeutic pharmacokinetics and bioavailability remain…
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