Myo10-dependent leading-edge coordination maintains physical coherence of migrating dendritic cells
Dendritic cells (DCs) are the principal leukocytes responsible for priming T cells. DC migration though geometrically complex tissue environments is crucial for initiating robust and spatiotemporally coordinated activation of adaptive immune responses. However, our understanding of the molecular mechanisms that govern physical navigation of DCs remains incomplete. Here we identify the…
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