Extracellular HSPB1 protects intestinal epithelial cells against ethanol-activated ferroptosis
Alcohol consumption damages the gastrointestinal tract, the initial site of contact for ingested ethanol. Intestinal epithelial cells (IEC) lining the small intestine are at particular risk of ethanol toxicity since they are largely responsible for ethanol absorption and metabolize ethanol into toxic metabolites. These toxic metabolites generate oxidative stress that damages cellular components…
We haven't written up this one. bioRxiv has the full story — the link below goes straight to it.
