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Amygdala Persistence in Aging: Replication and Extension of Puccetti et al. (2021)

Age-related differences in affect are well established, but their neural mechanisms remain unclear. In a preregistered replication of Puccetti et al. (2021) and extension, we examined age, affect, left-amygdala negative persistence, and amygdala-ventromedial prefrontal cortex (vmPFC) task-based connectivity using MIDUS 3 daily diary and fMRI data. Older age predicted higher positive and lower…

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