A spatial and single-cell transcriptomic atlas of the embryonic synovial joint and its explant model
Synovial joint formation requires the coordinated differentiation of multiple cell types while balancing opposing migratory cues that recruit joint progenitors and exclude other populations. More specifically, a subset of limb bud mesenchyme is recruited into the interzone while neighboring chondrocytes and endothelial cells are excluded. Existing single-cell references sample this process…
We haven't written up this one. bioRxiv has the full story — the link below goes straight to it.
