Evolution of histone mRNA 3' end processing machinery in eukaryotes
Replication-dependent histone mRNAs in metazoans terminate in a conserved 3' stem-loop (SL) recognized by stem-loop binding protein (SLBP) and processed by a specialized U7 snRNP-dependent cleavage machinery. Outside animals, the evolutionary history of this pathway remains poorly resolved, and fungi and most plants are widely thought to have lost SLBP-SL-dependent histone mRNA processing…
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