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Diverse stresses converge on bacterial periplasmic expansion through distinct physiological mechanisms

Diverse environmental and antibiotic stresses induce localized periplasmic expansion, the separation of the inner membrane from the cell wall and outer membrane, in Gram-negative bacteria, yet whether these morphologically similar responses arise through a common mechanism remains unclear. Here, we compare periplasmic expansion induced by sudden starvation, ciprofloxacin, mitomycin C, and…

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