Collateral effects of bacteriophage resistance on antibiotic sensitivity in Pseudomonas aeruginosa

Collateral effect (CEs) of phage resistance can alter antibiotic sensitivity, leading to collateral sensitivity (CS). CS of phage resistance can potentially be used to design more effective phage--antibiotic combination treatments, yet insufficient knowledge on the occurrence of such phage resistance associated CS is currently available. Here, we characterized CEs across diverse Pseudomonas…

biorxiv.org ·1d ago

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