Microglia-derived Small Extracellular Vesicles Promote Bone Marrow Monocyte Expansion and Recruitment in Glioblastoma.
Glioblastoma (GBM) remains one of the deadliest human cancers and is characterized by a profoundly immunosuppressive tumor microenvironment (TME). Although tumor-associated microglia (TAMg) promote GBM progression, their role in regulating immune cell recruitment remains poorly understood. Here, we demonstrate that TAMg-derived small extracellular vesicles (sEVs) mediate bone marrow-derived…
We haven't written up this one. bioRxiv has the full story — the link below goes straight to it.
