Engineered cells that sense and respond to interleukin-23 with neutralizing therapy for autoimmunity
Engineered cell sensors are powerful tools for monitoring biomarkers and delivering timely therapy. Here we create an engineered cell sensor of interleukin-23 (IL-23), a critical biomarker in many autoimmune diseases, and a therapeutic delivery platform for autoimmune disease management. We utilized Modular Extracellular Sensor Architecture (MESA), a promising platform given its modularity and…
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