College football picks: Ohio State’s Ryan Day is an old hand when it comes to top-five matchups

Week 7 of the college football season is shaping up to be the best yet with six games featuring teams ranked in The Associated Press Top 25. This includes a top-five showdown between No. 4 Ohio State and No. 5 Indiana, as well as a top-10 matchup between No. 2 Notre Dame and No. 8 BYU.

Ohio State, the reigning national champion, hosts Indiana, aiming to secure a spot in the Big Ten championship game and improve its College Football Playoff seeding. Meanwhile, Notre Dame travels to BYU, marking the first top-10 game at LaVell Edwards Stadium. Neither team has faced a particularly challenging schedule thus far, but this game carries significant playoff implications.

On the other side of the field, No. 16 Mississippi State travels to No. 22 LSU, where a Bulldogs victory would effectively kill LSU's playoff hopes. Also noteworthy is the clash between No. 6 Alabama and No. 14 Tennessee, with Alabama looking to bounce back from its home loss to Georgia. In a Missouri-Tennessee matchup, Missouri quarterback Austin Simmons has stepped aside for Trinidad Chambliss, who remains the starter at Mississippi.

Not to be overlooked is the Big 12 game between No. 18 Oklahoma State and No. 20 Houston, where the Cowboys have emerged as an unexpected success story after a recent four-game win streak. Finally, No. 4 Ohio State faces No. 5 Indiana at noon ET, with the Buckeyes having won four straight games since their fourth-quarter meltdown against Texas.