Astrocyte fatty acid uptake and ketogenesis in the mediobasal hypothalamus coordinate adaptive metabolic responses against high-fat diet exposure in male rodents
The mediobasal hypothalamus (MBH) constitutes a central regulator of energy homeostasis; specialized neurons in this region integrate peripheral metabolic signals to coordinate processes like food intake, energy expenditure or glucose homeostasis. While MBH neuronal dysfunction has been linked to obesity, increasing evidence indicates that astrocytes in this region are also active participants in…
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