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A silent intergenic locus for efficient and versatile transgene expression in Plasmodium falciparum

Genetically modified Plasmodium falciparum parasites expressing transgenes such as fluorescent markers are crucial tools for malaria research. However, current reporter lines often rely on integrated transgene constructs that disrupt the coding sequence of a native gene, potentially affecting progression in the life cycle of the tool parasite line. We identified six candidate Silent Intergenic…

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