A Multiverse Approach to Brain Age Prediction: Exploring the Impact of Modality, Bias Adjustment, and Atlas
Brain age, an individual's age predicted from neuroimaging data, is a promising biomarker of brain health. Yet brain age estimates may depend on methodological choices within the prediction pipeline. We used a multiverse approach to systematically investigate effects of data modality, bias-adjustment method, and brain parcellation on brain-age prediction using data from 560 healthy adults…
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