Concurrent de novo inference of cell types and gene regulatory networks with NetMap
Existing methods for GRN inference based on single-cell RNA-sequencing (scRNA-seq) data typically require prior cell type calling and then infer GRNs at cell type resolution. This risks propagation of errors from cell annotation to GRN inference. Moreover, it makes existing methods blind to regulatory programs that are shared between different cell types, as well as to subtle differences in…
We haven't written up this one. bioRxiv has the full story — the link below goes straight to it.