PFT's Week 5 2026 NFL picks

Week 5 of the NFL season has some intriguing matchups. In the Week 4 standalone games, the reporter had a 10-6 record, better than his 8-8 mark from Week 3. The Week 5 picks start with the Buccaneers facing the Cowboys in a Thursday night game. The reporter believes rookie Jalon Daniels could make a big impact if the Cowboys underestimate the Buccaneers.

Next up is the Eagles vs. Jaguars in London, where the Eagles have struggled due to injuries and roster changes. The Jaguars, however, see this as an early bye week opportunity. In a divisional game, the Bears are favored over the Packers, despite the absence of starting quarterback Caleb Williams. The Bengals are expected to defeat the Dolphins, who have been inconsistent this season.

The Raiders will face the Patriots, who have shown they can be dangerous even after recent setbacks. The Vikings are seen as the stronger team over the Saints. The Browns are predicted to win against the Jets. The Colts are given a slight edge over the Steelers, thanks to a favorable schedule for Pittsburgh. The Texans are expected to lose to the Titans, a game not even The Weather Channel wants to televise.

The Commanders are favored over the Giants, with Jayden Daniels' return potentially giving them a boost. The Broncos are expected to win against the Chargers, as Sean Payton tries to get back into calling plays. The Lions are predicted to narrowly edge out the Cardinals. The Seahawks aim to avoid falling too far behind the 49ers, while the Ravens are expected to lose to the Falcons.

Finally, the Bills face the Rams in a potential Super Bowl preview, with the outcome hinging on whether the Rams can maintain their recent winning form.