Neuropeptide NLP-40 and Cognate G- Protein Coupled Receptor AEX-2 Regulate Behavioral Responses During Anoxia in Caenorhabditis elegans
Background: Insufficient oxygen (hypoxia) or complete lack of oxygen (anoxia) causes cellular dysfunction and death in terrestrial animals. As a result, animals have developed homeostatic strategies, including changes in movement strategies to escape and survive stressful environments. Caenorhabditis elegans respond to changes in oxygen by increasing the frequency of reversals (backward movement)…
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