msengine: Adaptive Open-Source Signal Extraction for HDX MS
Hydrogen-deuterium exchange mass spectrometry (HDX-MS) requires extraction of broad, time-dependent peptide isotope envelopes from noise and overlapping signals. The ExMS/ExMS2 lineage established a retention-time-aware framework for raw-data extraction and integrated HDX-MS analysis. Building on this foundation, msengine is an open-source Python engine that adapts mass-selection windows and…
We haven't written up this one. bioRxiv has the full story — the link below goes straight to it.
