NFL betting, odds, lines: Betting trends to know for Week 5's biggest games

In the upcoming NFL Week 5, there are several intriguing matchups to consider for bettors. The Eagles enter their clash against the Jaguars with a daunting 0-4 ATS start, having only won 11 of their last 12 games. This marks the first time in franchise history that Philadelphia cannot cash as a 3.5-point home underdog. Meanwhile, the Jaguars have been on a 11-1 win and ATS streak, tallying eight wins by 14 points or more.

The odds for the game are as follows: Eagles -7.5 and 42, while the Jaguars are +7.5 and -355. The moneyline shows Philadelphia at +280 and Jacksonville at -355. The Eagles' recent performance against the Rams, where they gave up two touchdowns in the final four minutes of a 24-20 loss, has left them in a 0-4 ATS start at home. In contrast, the Jaguars have been unstoppable in their last 11 meetings, winning all while covering the spread.

Another notable game is the Raiders versus the Patriots, where the Raiders are coming off a 30-27 loss to Kansas City in Week 4. The Raiders are riding a strong 6-1 ATS record overall, including 6-1 ATS as an underdog and 3-0 ATS as a visitor. The Patriots, on the other hand, have been dominant in recent matchups against the Raiders, with a 3-0 SU and ATS record since 2022. The odds for this game are Raiders +165 and Patriots -200.

Lastly, the Bears and Packers face off in an NFC North rivalry. Chicago has had a difficult start to the season, losing their last three games to the Bears and Packers, but still maintaining a 3-1 SU and ATS record. Green Bay, despite a loss to Atlanta, has benefitted from favorable NFL betting trends, with a 30-8 SU and 26-11-1 ATS record against the Bears since 2008, including 15-3 SU and 12-5-1 ATS at Lambeau Field. The odds for this game are Bears -2.5 and 45.5, while the Packers are +125.