Detached Nails More Than 4 Times Higher Among GLP-1 Users, Study Finds
In a new study, GLP-1 users reported nail detachment more than four times as often as nonusers. Waishaw/Getty Images GLP-1 drugs like Ozempic have been linked to unusual nail changes in a new study. GLP-1 users reported nail detachment more than four times as often as nonusers, and nail discoloration affected 46% of GLP-1 users, compared with 17% of nonusers. The differences held up among people…
A new study has found that users of GLP-1 drugs, such as Ozempic and Wegovy, experience nail detachment at a rate more than four times higher than non-users. GLP-1 users reported nail detachment in 39% of cases, compared to 9% of non-users. Nail discoloration was reported by 46% of GLP-1 users, while 17% of non-users experienced this side effect.
The differences were consistent even when considering people who had lost weight, suggesting that weight loss alone may not be the cause of these issues. The study, presented at the European Academy of Dermatology and Venereology (EADV) Congress 2026 in Vienna, also found that hair loss is a common side effect of GLP-1 drugs. Experts advise taking measures to maintain skin and hair health while using these medications.
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