Global and regional reference curves for pain across the lifespan in 6.1 million individuals in 118 countries
Nature Medicine, Published online: 05 October 2026; doi:10.1038/s41591-026-04696-w Global age- and sex-specific reference curves for 11 pain sites, from 6.1 million people in 118 countries, found higher late-life pain in the lowest Human Development Index (HDI) countries and provide a tool for benchmarking pain assessments in other cohorts.
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