Florida vs South Carolina: Odds, injuries, predictions and key matchups

Florida football is set to face South Carolina in their Homecoming Game on October 10 at Ben Hill Griffin Stadium. The No. 15 Florida Gators (2-3, 0-3 SEC) are coming off a first loss of the season, a 45-17 defeat to Missouri, which exposed weaknesses in their secondary and pass defense. The South Carolina Gamecocks (2-3, 0-3 SEC) will pose a challenge to Florida's defensive backs.

South Carolina's quarterback LaNorris Sellers has thrown for 1,059 yards with 8 touchdowns and 4 interceptions, while receiver Nyck Harbor, 6-foot-5 and 239 pounds, is a formidable target with 13 catches for 195 yards and 1 touchdown. Florida holds a strong record in Homecoming Games, winning 31 of 35 since 1989. In their last homecoming game, they defeated Mississippi State 23-21.

Florida football injury update: Wide receiver Vernell Brown III (knee) did not fully participate in practice on Monday, October 5 but is trending positively and will do a running session with the training staff later. Safety Bryce Thornton, who suffered a lower body injury, is also expected to play after imaging revealed no structural damage.

The game will be broadcast on the SEC Network, streamed on Fubo and ESPN+, and will take place at Ben Hill Griffin Stadium in Florida, known as "The Swamp". The betting odds have Florida as favorites with a spread of -13.