Large analysis finds no clear link between rotavirus vaccination and type 1 diabetes
New research presented at the annual meeting of the European Association for the Study of Diabetes (EASD) in Milan, Italy (Sept. 28–Oct. 2), and published in Diabetologia shows that the incidence (the new case rate) of type 1 diabetes (T1D) in children ages 0.5–5 years in Norway was 11% higher following the rapid rollout and uptake of the rotavirus vaccine in September 2014. The study is by…
A comprehensive study presented at the European Association for the Study of Diabetes meeting in Milan found no clear link between the introduction of the rotavirus vaccine in Norway in 2014 and an increase in type 1 diabetes (T1D) among children aged 0.5-5 years. Researchers compared the incidence of T1D in children born before and after the vaccine rollout, finding an 11% higher incidence following the vaccine's introduction.
While adjusted analyses showed a relative increase of 11% and a hazard ratio of 1.17 for fully vaccinated children, these results were not statistically significant. The authors suggest that the increase in T1D incidence might be due to other, unknown environmental changes, as similar patterns were observed after unrelated vaccine changes.
The study also considered potential explanations such as the COVID-19 pandemic and changes in prenatal follow-up guidelines, but found no conclusive evidence linking these factors to the rise in T1D cases.
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