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Inhibitory budget matching constrains homeostatic plasticity in competitive spiking networks

Competitive spiking networks can form sensory representations through local synaptic plasticity and lateral inhibition. A canonical example is the Diehl-Cook architecture, in which Poisson-encoded sensory inputs drive excitatory neurons through spike-timing-dependent plasticity (STDP), while a separate inhibitory population imposes competition between excitatory units. In most implementations…

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Proteomics Maps Eye-Infecting Acanthamoeba Mitochondria Across Oxygen Levels

A new catalog of 1,122 mitochondrial proteins reveals how Acanthamoeba adapts to oxygen loss—and may highlight possible targets for treating sight-threatening infections.

  • Acanthamoeba mitochondria adapt to low oxygen by producing hydrogen gas
  • Researchers map 1,122 proteins, 381 unique to Acanthamoeba
  • Study in Cell improves understanding of amoeba's metabolic flexibility

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