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Distinct population dimensions separate sensory adaptation and expectation-related signals in visual cortex

Mismatch negativity is conventionally quantified as a scalar response-amplitude difference between rare deviant and repeated standard stimuli, leaving its organization at the neuronal population level unresolved. We recorded population activity in mouse primary visual cortex (V1) during visual oddball and control paradigms while testing contributions from anterior cingulate cortex (ACC) input…

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Proteomics Maps Eye-Infecting Acanthamoeba Mitochondria Across Oxygen Levels

A new catalog of 1,122 mitochondrial proteins reveals how Acanthamoeba adapts to oxygen loss—and may highlight possible targets for treating sight-threatening infections.

  • Acanthamoeba mitochondria adapt to low oxygen by producing hydrogen gas
  • Researchers map 1,122 proteins, 381 unique to Acanthamoeba
  • Study in Cell improves understanding of amoeba's metabolic flexibility

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