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Consequences of sustained modulation of VIP-expressing neurons in mouse corticolimbic regions on anxiety-related avoidance behaviors, social functioning, and associative fear learning

GABAergic inhibitory neurons play a central role in shaping network dynamics, and accordingly, their dysfunction is implicated in the pathophysiology of various psychiatric, neurodevelopmental, and neurological disorders. In the past decade, studies on vasoactive intestinal polypeptide-expressing inhibitory neurons (VIP+ neurons) have positioned them as critical components of this circuitry. In…

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Proteomics Maps Eye-Infecting Acanthamoeba Mitochondria Across Oxygen Levels

A new catalog of 1,122 mitochondrial proteins reveals how Acanthamoeba adapts to oxygen loss—and may highlight possible targets for treating sight-threatening infections.

  • Acanthamoeba mitochondria adapt to low oxygen by producing hydrogen gas
  • Researchers map 1,122 proteins, 381 unique to Acanthamoeba
  • Study in Cell improves understanding of amoeba's metabolic flexibility

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