COVID-19 highlighted the need for antivirals that can be rapidly deployed against both current and future coronavirus threats. CMX990 is a clinical stage coronavirus main protease (Mpro) inhibitor bearing a unique trifluoromethoxymethyl ketone warhead. Here, we broadly evaluate its pan-coronavirus target engagement, antiviral breadth, and pharmacologic differentiation. Across a reporter panel of…
Two best friends decided to share one of their cancer journeys online, with hopes of spreading a message on friendship and healing. Tony Dokoupil has the story.
Almost 95% of viral Korean skin care and "glass skin" TikTok videos contained at least one potentially misleading claim, while basic safety information was largely absent, according to new research…
A single 20-minute session of alpha-frequency brain stimulation modestly reduced anxiety after a stressful task in healthy middle-aged and older adults.