Fractional Order Temporal Dynamics of Tumor Immune Chemotherapy Interactions: A Reproducible Dimensionless Analysis and a Pharmacokinetic Caveat
Fractional differential equations are increasingly used to represent temporal memory in tumour immune and pharmacokinetic models, but changing the derivative order without a consistent time scale can make comparisons difficult to interpret. We study a dimensionless, commensurate Caputo system for tumour, immune, normal cell, and drug states. We establish positivity, boundedness, the tumour…
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