Could ‘sea squirts’ hold a clue to healthier ageing?

Grey hair, memory loss, and physical decline are common signs of aging. However, a peculiar marine creature, known as sea squirts, may provide scientists with insights into slowing or even reversing some aspects of aging. Researchers have been examining compounds called plasmalogens, which are naturally present in humans and found in high concentrations in sea squirts.

These marine animals, belonging to the class Ascidiacea, are typically not consumed in Malaysia but are eaten in Japan and South Korea. A recent study indicated that plasmalogen supplements were associated with improved memory, healthier brain cell connections, and reduced inflammation in the brain. In the study, older mice treated with plasmalogen supplements exhibited better memory performance and displayed more youthful brain characteristics compared to untreated aging mice.

Although the research was conducted on mice and not humans, the potential of plasmalogens in brain health and aging remains promising. Plasmalogens are a type of fat molecule found in cell membranes, particularly abundant in the brain, heart, and immune cells. Their levels tend to decline with age, and lower levels have been observed in neurodegenerative conditions such as Alzheimer's and Parkinson's disease.

The study found that plasmalogen supplements improved memory, brain cell connections, and reduced inflammation. The mice treated with supplements also had thicker, glossier, and darker hair, though this effect is not indicative of a cure for aging or grey hair. It is crucial to note that animal studies provide valuable insights into biological mechanisms but may not always translate to human applications.

Further clinical trials are necessary to determine the safety and efficacy of plasmalogen supplements in improving cognitive function in humans, as well as to assess any potential long-term risks.