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Chromosomal breakage in Arabidopsis thaliana neo-polyploids occurs preferentially at candidate fragile sites colocalized with ancient genome rearrangements

Newly formed polyploids often suffer extensive aneuploidy and chromosome rearrangement. We explored whether these are predictable and conserved across genotypes. We quantified whole-chromosome and segmental aneuploidy in progeny arrays of neo-polyploid Arabidopsis thaliana from two accessions (Col-0 and Ler). 29% of progeny had whole-chromosome and/or segmental aneuploidies. Strikingly, segmental…

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